About this trial
The goal of this novel study is to compare the effect of a combined cognitive rehabilitation and exercise approach on new learning and memory (NLM) in persons with multiple sclerosis (pwMS) and mobility disability.
Eligibility criteria
Qualifiers
Be within the ages of 18 and 70 years of age
Speak English as their primary language
Confirmed MS diagnosis by a neurologist
Be relapse and steroid-free for at least 30 days
Disqualifiers
History of neurological disorders besides MS or history of uncontrolled psychiatric disorders (ex: major depression)
Have contraindications to exercise, based on the Physical Activity Readiness Questionnaire (PAR-Q)
Currently use medications that may impact cognition (ex: steroids, benzodiazepines)
Currently pregnant
Trial design
Treatments tested in this trial
- The Kessler Foundation modified Story Memory Technique® (KF-mSMT®)
- Aerobic Exercise Training (AET) plus Virtual Reality (IDEAL)
- Stretching and Toning (S/T)
Treatment groups
Sponsors and collaborators
Kessler Foundation
Lead sponsor
National Multiple Sclerosis Society
Collaborator