A Novel Combinatory Approach to Maximize Functional Recovery of Learning and Memory in Multiple Sclerosis

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorKessler Foundation

About this trial

The goal of this novel study is to compare the effect of a combined cognitive rehabilitation and exercise approach on new learning and memory (NLM) in persons with multiple sclerosis (pwMS) and mobility disability.

Eligibility criteria

Qualifiers

Be within the ages of 18 and 70 years of age

Speak English as their primary language

Confirmed MS diagnosis by a neurologist

Be relapse and steroid-free for at least 30 days

Disqualifiers

History of neurological disorders besides MS or history of uncontrolled psychiatric disorders (ex: major depression)

Have contraindications to exercise, based on the Physical Activity Readiness Questionnaire (PAR-Q)

Currently use medications that may impact cognition (ex: steroids, benzodiazepines)

Currently pregnant

Trial design

Treatments tested in this trial

  • The Kessler Foundation modified Story Memory Technique® (KF-mSMT®)
  • Aerobic Exercise Training (AET) plus Virtual Reality (IDEAL)
  • Stretching and Toning (S/T)

Treatment groups

78 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Kessler Foundation

Lead sponsor

National Multiple Sclerosis Society

Collaborator