A Pilot Study of Transcranial Magnetic Stimulation Plus Episodic Future Thinking for Methamphetamine Use Disorder

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorThe University of Texas Health Science Center, Houston

About this trial

The purpose of this study is to assess impact of repetitive transcranial magnetic stimulation (rTMS)+Episodic Future Thinking (EFT) vs. sham rTMS+EFT on delay discounting and methamphetamine (MA) demand, on vividness of future positive events during EFT training and on frequency of episodic thinking during the week following EFT training

Eligibility criteria

Qualifiers

Meet Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria for primary methamphetamine use disorder

Be fluent in English and able to understand the consent form

Disqualifiers

Current DSM-5 diagnosis for any illicit substance use disorder other than methamphetamine and marijuana

Current DSM-5 diagnosis of moderate or greater severity for alcohol and marijuana use disorder

In the opinion of the PI, the presence of any medical, neurological, psychiatric (e.g., psychotic or bipolar disorder), or physical condition, disease, or illness that, may: (a) compromise, interfere, limit, effect or reduce the subject's ability to complete the study; or (b) adversely impact the safety of the subject or the integrity of the data

Structured Clinical Interview for DSM-5 (SCID-5)

Trial design

Treatments tested in this trial

  • EFT
  • high frequency rTMS
  • sham frequency rTMS

Treatment groups

20 Participants
are divided into 2 treatment groups