A Prospective Single-Arm Observational Study of Maribavir for the Treatment of Post Hematopoietic Stem Cell Transplantation Cytomegalovirus Infection

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age12+
SponsorInstitute of Hematology & Blood Diseases Hospital, China

About this trial

The main aim of this study is to check the effectiveness and safety of maribavir for the treatment of CMV infection after HSCT in Chinese patients in real-world settings.

The participants will be treated with maribavir for up to 8 weeks.

Eligibility criteria

Qualifiers

Hematopoietic Stem Cell Transplant Recipients

Adult patients with an expected survival of ≥4 weeks.

Confirmed CMV infection, including CMV viremia and CMV disease.

Fully understand the content of the trial, voluntarily participate and complete the trial, and voluntarily sign the informed consent form.

Disqualifiers

Patients currently participating in other CMV-related clinical studies, such as those receiving anti-CMV drug treatment or involved in CMV vaccine clinical studies.

At screening, liver function tests show: AST > 5×ULN, or ALT > 5×ULN, or total bilirubin ≥ 3.0×ULN.

Patients with psychiatric disorders or severe psychological conditions that may affect the ability to provide informed consent or participate in follow-up consultations.

Participants deemed unsuitable for inclusion by the investigator.

Trial design

Treatments tested in this trial

  • maribavir

Treatment groups

17 Participants
are divided into 1 treatment group