About this trial
This study aims to investigate the best strategy for repeat ablation of recurrent persistent atrial fibrillation (AF) after previous persistent AF ablation involving pulmonary vein isolation (PVI) along. Patients with low voltage areas on the posterer wall will be randomized to PVI alone or the posterer wall isoaltion (PWI) in addition to PVI.
Eligibility criteria
Qualifiers
Symptomatic patients with persistent AF and indication for repeat ablation
procedure.
Patients with recurrent persistent AF (with a duration <3 year, at least one episode longer than 7 days during the last 6 months and have been electrically cardioverted at least once during the last 12 months) after previous catheter ablation.
Patients with up to two previous catheter ablations for AF are included if the procedures only involved PVI. Previous PVI procedure(s) with both cryoablation and radiofrequency ablation are accepted.
Disqualifiers
Patients with >2 ablation procedures in the LA for AF or atrial flutter
Previous ablation procedures for AF involving ablation strategies beyond PVI
Duration of persistent AF >3 years
Presence of atrial flutter or atrial tachycardia
Trial design
Treatments tested in this trial
- Radio frequency ablation
Treatment groups
Locations
Sponsors and collaborators
Haukeland University Hospital
Lead sponsor
St. Olavs Hospital
Collaborator
University Hospital of North Norway
Collaborator