A prospective, multicenter, randomized controlled, open-label, blinded outcome evaluation (PROBE) trial
Age ≥ 18 years
National Institutes of Health Stroke Scale (NIHSS) score ≥6 before randomization
To receive mechanical thrombectomy <24 hours after AIS onset according to local guidelines
Signed informed consent form obtained from the subject (or approved surrogate)
Pre-stroke mRS >2
Intracranial hemorrhage confirmed by CT before mechanical thrombectomy and enrolment
Suspected Intracranial hemorrhage after successful recanalization confirmed by 3D-CT
Tandem lesions: stenosis (or occlusion) of the extracranial segment of the internal carotid artery or vertebral artery combined with occlusion of large intracranial vessels, stenosis of intracranial arteries combined with occlusion of vessels distal to the stenosis
Changhai Hospital
Lead sponsor
The First People's Hospital of Changzhou
Collaborator