About this trial
The goal of this randomized clinical trial is to compare the effects of an online mindfulness program to an active supportive comparison condition and a no-intervention control group on reducing and preventing mood and anxiety symptoms in at-risk youth. Youth who are high on trait negative affect will be randomized to one of the three conditions. The primary outcomes of interest are reductions in momentary negative affect and internalizing problems in adolescents ages 12 to 17 years old. All participants will be evaluated prior to being randomized, after the 9-session intervention period, and at a 6-month follow-up.
The first hypothesis is that the mindfulness intervention will predict decreases in stressor-reactive momentary negative affect and internalizing symptoms. The second hypothesis is that changes in momentary negative affect will partially account for the effects of the mindfulness intervention on internalizing symptoms.
Eligibility criteria
Qualifiers
Ages 12, 13, 14, 15, 16, 17
Parental Consent
Participant Assent
Live in Illinois, California, or Tennessee
Disqualifiers
current diagnosis of an anxiety or depressive disorder with significant clinical impairment
current alcohol or substance use disorder
current serious suicidal ideation or behavior
lifetime diagnosis of bipolar disorder, schizophrenia, autism, conduct disorder, or developmental delay
Trial design
Treatments tested in this trial
- Mindfulness Program
- Active Comparator
Treatment groups
Sponsors and collaborators
Vanderbilt University
Lead sponsor
National Institute of Mental Health (NIMH)
Collaborator