A Randomized Trial of a Mobile Health Exercise Intervention for Older Adults With Myeloid Neoplasms
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age60+
SponsorUniversity of Rochester
About this trial
This is a phase 2 randomized controlled trial (RCT) to assess the preliminary efficacy of the a mobile health exercise intervention (GO-EXCAP) versus a chemotherapy education control in 100 older patients with MN receiving outpatient chemotherapy on physical function and patient-reported outcomes (fatigue, mood, and quality of life). We will also explore the effect of the intervention on TNFα and related cytokine gene promoter methylation and their gene and protein expression.
Eligibility criteria
Qualifiers
Age ≥60 years (conventional definition of older age in clinical trials of MN)
Have a diagnosis of MN
Planned for or receiving outpatient cancer-directed treatments (participants receiving consolidative or maintenance outpatient therapies after induction chemotherapy are allowed to enroll)
English speaking
Disqualifiers
Physical, psychological, or social impairments that would interfere with subject's ability to participate in the study or participate in the intervention, as determined by the PI or the treating team
Trial design
Treatments tested in this trial
- GO-EXCAP Mobile App
- Behavioral Placebo Control
Treatment groups
170 Participants
are divided into 2 treatment groupsSponsors and collaborators
University of Rochester
Lead sponsor
National Cancer Institute (NCI)
Collaborator
Source ClinicalTrials.gov