A Real-World Study on Hypertrophic Cardiomyopathy in Chinese Population

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University

About this trial

This study is a prospective cohort study aimed at exploring the baseline characteristics and treatment patterns of the Chinese population with hypertrophic cardiomyopathy (HCM) in real-world settings. The objective is to assess the real-world treatment approaches and longitudinal outcomes in this population.

Eligibility criteria

Qualifiers

Willing and able to provide written informed consent (ICF) and any required privacy authorization before the start of the study.

Aged ≥18 years at the time of signing the written informed consent.

Left ventricular wall thickness ≥15 mm in any segment at end-diastole, as assessed by echocardiography or cardiac magnetic resonance imaging (MRI).

Left ventricular wall thickness ≥13 mm in individuals with a positive pathogenic gene test or those identified as members of a genetically affected family.

Disqualifiers

Uncontrolled primary hypertension.

Moderate or severe aortic valve stenosis and/or primary mitral valve disease with severe mitral regurgitation.

Confirmed infiltrative or storage diseases with a phenotype resembling hypertrophic cardiomyopathy (e.g., Fabry disease, amyloidosis).

Expected life expectancy <1 years.

Trial design

Treatments tested in this trial

  • No interventions were applied to the patients.

Treatment groups

3,000 Participants
are divided into 1 treatment group