About this trial
The aim of this study is to determine the clinical spectrum and natural progression of Hereditary Spastic Paraplegias(HSP) and related disorders in a prospective multicenter natural history study, to assess the clinical, genetic and epigenetic features of patients with Spastic Paraplegias to optimize clinicalmanagement..
Eligibility criteria
Qualifiers
Patients with the clinical diagnosis of spastic paraplegia
Clinical diagnosis of patients with spastic paraplegia
Unrelated healthy controls
Disqualifiers
Decline to participate.
There are serious interferences with individual participation and adherence to the research protocol, including but not limited to neurological, psychological, and/or medical conditions.
Trial design
Treatments tested in this trial
Treatment groups
Sponsors and collaborators
Wan-Jin Chen
Lead sponsor
First Affiliated Hospital of Fujian Medical University
Sponsor institution