A Study Looking at a New Nerve Surgery to Help Men Regain Erections After Prostate Cancer Surgery

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age18+
SponsorSir Mortimer B. Davis - Jewish General Hospital

About this trial

A single arm prospective pilot trial evaluating the 1-year erectile recovery outcomes and the safety of patients undergoing a somatic to autonomic nerve grafting procedure for restoration of erectile function in patients who have lost erectile function following radical prostatectomy for prostate cancer. During this study a total of 100 patients who have persistent erectile dysfunction for more than 18 months post prostatectomy will undergo a post radical prostatectomy nerve restoration procedure (PRP-NR).

Eligibility criteria

Qualifiers

Severe ED (IIEF score 5-7) and more than 12 months from prostatectomy OR

Moderate ED (IIEF score 8-11) and more than 18 months from prostatectomy

Patients must have had good pre-prostatectomy erectile function with a baseline IIEF score of ≥17 on self-reported assessment of historic function.

Disqualifiers

Patients aged < 18 years at diagnosis

Legally incapable patients

Patients >5 years from prostatectomy.

Bilateral open inguinal hernia repair

Trial design

Treatments tested in this trial

  • Post radical prostatectomy nerve restoration procedure (PRP-NR)

Treatment groups

100 Participants
are divided into 1 treatment group

Sponsors and collaborators

Sir Mortimer B. Davis - Jewish General Hospital

Lead sponsor

McGill University Health Centre/Research Institute of the McGill University Health Centre

Collaborator

Western University, Canada

Collaborator

Fox Chase Cancer Center

Collaborator