About this trial
A single arm prospective pilot trial evaluating the 1-year erectile recovery outcomes and the safety of patients undergoing a somatic to autonomic nerve grafting procedure for restoration of erectile function in patients who have lost erectile function following radical prostatectomy for prostate cancer. During this study a total of 100 patients who have persistent erectile dysfunction for more than 18 months post prostatectomy will undergo a post radical prostatectomy nerve restoration procedure (PRP-NR).
Eligibility criteria
Qualifiers
Severe ED (IIEF score 5-7) and more than 12 months from prostatectomy OR
Moderate ED (IIEF score 8-11) and more than 18 months from prostatectomy
Patients must have had good pre-prostatectomy erectile function with a baseline IIEF score of ≥17 on self-reported assessment of historic function.
Disqualifiers
Patients aged < 18 years at diagnosis
Legally incapable patients
Patients >5 years from prostatectomy.
Bilateral open inguinal hernia repair
Trial design
Treatments tested in this trial
- Post radical prostatectomy nerve restoration procedure (PRP-NR)
Treatment groups
Sponsors and collaborators
Sir Mortimer B. Davis - Jewish General Hospital
Lead sponsor
McGill University Health Centre/Research Institute of the McGill University Health Centre
Collaborator
Western University, Canada
Collaborator
Fox Chase Cancer Center
Collaborator