A Study of Body Fat Distribution and Airway Mechanics in Healthy Adults

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorMaurizio F. Cereda, MD

About this trial

This study investigates how body fat distribution affects airway closure and lung mechanics in healthy adults. Using Electrical Impedance Tomography (EIT), esophageal manometry, and computed tomography (CT), we aim to characterize how varying BMI and fat topography influence regional ventilation and airway collapse in supine and prone positions. Healthy volunteers with a range of BMIs will undergo a 2-hour imaging session with noninvasive and minimally invasive monitoring.

Eligibility criteria

Qualifiers

None

Disqualifiers

Pre-existing cardiopulmonary disease

history of tobacco or ecigarette smoking

Trial design

Treatments tested in this trial

  • Body positioning

Treatment groups

20 Participants
are divided into 1 treatment group

Locations

This trial has no locations

Sponsors and collaborators

Maurizio F. Cereda, MD

Lead sponsor

Massachusetts General Hospital

Sponsor institution

National Institutes of Health (NIH)

Collaborator