A Study of Body Fat Distribution and Airway Mechanics in Healthy Adults
ConditionHealthy Volunteers Only
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorMaurizio F. Cereda, MD
This study investigates how body fat distribution affects airway closure and lung mechanics in healthy adults. Using Electrical Impedance Tomography (EIT), esophageal manometry, and computed tomography (CT), we aim to characterize how varying BMI and fat topography influence regional ventilation and airway collapse in supine and prone positions. Healthy volunteers with a range of BMIs will undergo a 2-hour imaging session with noninvasive and minimally invasive monitoring.
None
Pre-existing cardiopulmonary disease
history of tobacco or ecigarette smoking
Maurizio F. Cereda, MD
Lead sponsor
Massachusetts General Hospital
Sponsor institution
National Institutes of Health (NIH)
Collaborator