A Study on Factors of Biochemical Response in Autoimmune Hepatitis
ConditionAutoimmune Hepatitis
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorBeijing Friendship Hospital
About this trial
The goal of this observational study is to clarify the clinical characteristics of autoimmune hepatitis (AIH) in China. The main questions it aims to answer are:
Human leukocyte antigen (HLA) gene susceptibility in Chinese AIH patients prognostic factors associated with AIH Participants will provide liver tests results and details of treatment during follow-up.
Eligibility criteria
Qualifiers
≥18 years old at the time of onset;
AIH simplified score ≥6 and/or AIH revised score ≥10;
Liver biopsy was performed and consistent with the pathological diagnosis of AIH;
Patents were treatment naive or who were diagnosed and treated in other hospitals but have stopped glucocorticoid/immunosuppressive therapy for more than 3 months;
Disqualifiers
concomitant liver diseases: hepatotropic viral hepatitis (A, B, C, D, and E) and non-hepatotropic viral hepatitis (cytomegalovirus and Epstein-Barr virus (EBV) infection);
concomitant with drug-induced liver injury, primary biliary cholangitis, primary sclerosing cholangitis, alcoholic liver disease, genetic and metabolic liver diseases;
bone marrow or liver transplantation;
incomplete baseline medical history and laboratory examination results;
Trial design
Treatments tested in this trial
- Not listed
Trial groups
630 Participants
are grouped into 2 trial groupsSponsors and collaborators
Source ClinicalTrials.gov