A Study on Relationship Between Resected Normal Liver Parenchymal Volume(RNLV)and Post-Hepatectomy Liver Failure (PHLF)

ConditionLiver Failure
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorNational Natural Science Foundation of China

About this trial

The post-hepatotectomy liver failure (PHLF) is still the most worrisome complication of hepatic resection. Surgeons have always been making efforts to preoperatively predict PHLF using kinds of techniques, scoring systems, and variables. The investigators of this study tried to create an individual predictive model based on the variable, resected normal parenchymal volume (RNLV), then assessing the performance and value of the model in clinical practice.

Eligibility criteria

Qualifiers

selective hepatectomies;

histologically confirmed as HCC and ICC

complete and accessible data

Disqualifiers

any history of Associated Liver Partition and Portal vein ligation for Staged hepatectomy (ALPPS)

any history of portal vein embolism (PVE)

any history of tumor rupture

emergency surgery

Trial design

Treatments tested in this trial

  • the different definitions of PHLF according to 50-50 criteria and ISGLS criteria

Treatment groups

1,600 Participants
are divided into 2 treatment groups