A Study on the Effect of High-concentrated Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base.

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeNot listed
SponsorKarolinska Institutet

About this trial

This is a randomized double-blinded randomized comparison between injection of platelet rich plasma (PRP) and placebo for thumb basale osteoarthritis.

Eligibility criteria

Qualifiers

Osteoarthritis in the thumb base

Radiological Eaton Littler class 1-3.

Clinical signs of thumb base osteoarthritis )pain at palpation of the CMC-1 joint and pain during provocation/grinding test).

Disqualifiers

Rheumatoid arthritis

Ongoing infection in the hand or wrist

History of gout or pseudogout in the hand

Inability to co-operate with the follow-up protocol (language difficulties, severe psychiatric disorder, cognitive impairment, drug addiction).

Trial design

Treatments tested in this trial

  • Platelet rich plasma (PRP)
  • Placebo

Treatment groups

90 Participants
are divided into 2 treatment groups

Sponsors and collaborators