A Study to Analyze the Role of Sympathetic Nervous System in Spontaneous Coronary Artery Dissection
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18+
SponsorMayo Clinic
About this trial
The purpose of this research is to compare sympathetic function (flight or fight system) and arterial health including structure and mechanics of participants with history of spontaneous coronary artery dissection (SCAD) to age and sex matched control participants.
Eligibility criteria
Qualifiers
For SCAD patients: history of SCAD as confirmed by coronary angiography or cardiac computed tomography angiography
For controls: no cardiac disease history
Disqualifiers
Pregnancy
Known or suspected unstable cardiac condition within 4 weeks of the study
Active treatment with anticoagulation or dual antiplatelet therapy
Prisoner
Trial design
Treatments tested in this trial
- Arterial Tonometry
- Echocardiogram
- Carotid Ultrasounds
- Elastography
- Ankle-Brachial Index
- Microneurography with sympathoexcitatory maneuvers
Treatment groups
50 Participants
are divided into 2 treatment groupsSponsors and collaborators
Mayo Clinic
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Collaborator
Source ClinicalTrials.gov