A Study to Evaluate Effectiveness and Safety of a TYK2 Inhibitor in Subjects With Moderate to Severe Plaque Psoriasis

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorUsynova Pharmaceuticals Ltd.

About this trial

A Study to evaluate efficacy and safety in subjects with moderate to severe Plaque Psoriasis treated with a TYK2 Inhibitor for 12 weeks

Eligibility criteria

Qualifiers

Male and female, ages 18 to 70 years

Body weight >40 kg, body mass index (BMI) of 18 to 40 kg/m2

Clinical diagnosis of plaque psoriasis for ≥6 months before the Baseline visit

Women of childbearing potential (WOCBP) and males who are sexucally active must agree to follow instructions for method(s) of contraception.

Disqualifiers

Diagnosed with non-plaque psoriasis

Previously received tyrosine kinase 2 (TYK2) inhibitors

Previously received other psoriasis treatments such as biological agents, immunoregulators, or hormonal drugs within a specific period before administration, and the investigator deems it may affect the immunity of the subjects

Has participated in any clinical trials within 30 days or 5 half-lives of the drug before the first administration, or currently undergoing visits for other clinical trials;

Trial design

Treatments tested in this trial

  • Tyk2 inhibitor
  • Placebo

Treatment groups

140 Participants
are divided into 4 treatment groups

Sponsors and collaborators