This study is a prospective, single-center, randomized controlled trial focusing on patients with acute necrotizing pancreatitis (ANP) complicated by pancreatic sinistral portal hypertension (PSPH). The study aims to study the impact of total splenectomy on the debridement efficacy, perioperative recovery, and prognosis of patients with ANP complicated by PSPH.
Age between 18 and 75 years.
Acute necrotic pancreatitis complicated by pancreatic sinistral portal hypertension.
Patients undergoing open debridement for infected pancreatic necrosis
Patients with pre-existing heart, lung, liver, kidney, or other organ failure prior to acute pancreatitis (AP).
Patients with pre-existing conditions such as cirrhosis that may lead to portal hypertension prior to AP.
Patients with pre-existing hematological diseases prior to AP.
Patients undergoing laparoscopic or nephroscopic debridement.