A Study to Evaluate the Effectiveness and Safety of Polatuzumab in Real World Clinical Practice Among Adult Chinese Participants With Diffuse Large B-Cell Lymphoma

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorHoffmann-La Roche

About this trial

The purpose of this study is to assess the progression free survival (PFS) in the real-world settings of polatuzumab among Chinese diffuse large B cell lymphoma (DLBCL) participants.

Eligibility criteria

Qualifiers

Be diagnosed as DLBCL

Cohort 1: diagnosed as unfit/frail DLBCL. The unfit/frail is defined as aged 80 years or older, or younger than 80 years but with comorbidity and not tolerant to the standardized dose of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) therapy according to investigator's judgment

Cohort 2: diagnosis as DLBCL but could not be classified into unfit/frail

Cohort 3: relapse or refractory to previous treatment

Disqualifiers

Participant who currently participates in or with plan to participate in any interventional clinical trial

Any other reason that, in the investigator's opinion, makes the participant unsuitable to participate in this study.

Trial design

Treatments tested in this trial

  • Polatuzumab Vedotin

Treatment groups

1,000 Participants
are divided into 3 treatment groups

Sponsors and collaborators