A Study to Reduce Persistent Post-mastectomy Pain Using Opioid-free Anesthesia
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age19-80
SponsorGangnam Severance Hospital
About this trial
In 230 patients undergoing mastectomy, the investigators will compare opioid-free anesthesia (OFA) versus conventional opioid-based anesthesia in terms of chronic pain. The enrolled patients will be randomly assigned into two groups with 1:1 ratio. Chronic pain will be evaluated at 1 year after mastectomy based on the Breast Cancer Pain Questionnaire (BCPQ). Baseline pain sensitivity test and psychologic evaluation will be done before operation.
Eligibility criteria
Qualifiers
All of patients will undergo mastectomy with or without immediate breast reconstruction.
Disqualifiers
Previous history of breast surgery
Allergy to drug
Other cancer history
Underlying psychologic disorder
Trial design
Treatments tested in this trial
- Opioid-free anesthesia
- Conventional opioid-based anesthesia
Treatment groups
230 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov