Health Trials

A Study to Test the Diagnostic Potential of Brillouin Microscopy for Corneal Ectasia

ConditionsKeratoconusEctasiaCrosslinkingFuchs' Endothelial Dystrophy
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age20-75
SponsorMassachusetts General Hospital

About this trial

We have developed novel Brillouin microscopy and we are testing its potential for keratoconus and ectasia diagnostics. We plan to perform axial scans of the cornea in human volunteers in order to compare biomechanical properties of Keratoconus vs. Normal corneas and compare biomechanical properties of post-LASIK ectasia vs. normal corneas.

Eligibility criteria

Qualifiers

None

Disqualifiers

Have occludable narrow angles (without a patent peripheral iridotomy)

Monocular subjects

Do not or cannot understand the instructions for the imaging

Trial design

Treatments tested in this trial

  • Brillouin imaging

Treatment groups

168 Participants
are divided into 7 treatment groups

7

Treatment groups

See each treatment group below.

Sponsors and collaborators

Massachusetts General Hospital

Lead sponsor

Harvard Medical School (HMS and HSDM)

Collaborator

Source ClinicalTrials.gov