A Two-Part Intervention to Target Cardiovascular Health

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age9-26
SponsorUniversity of California, Los Angeles

About this trial

Obesity is one of the most common health conditions among autistic young people and its prevalence rises at faster rates for autistic-relative to non-autistic-individuals. This places them at heightened risk for cardiovascular disease (CVD) and mortality before they enter adulthood. Studies have identified three key contributing factors to CVD outcomes in autistic individuals: unhealthy lifestyle behaviors, Adverse Childhood Experiences (ACEs), and chronic stress.

This study will explore the effectiveness of two CVD-focused primary care interventions for autistic individuals (ages 9-26): (1) lifestyle medicine consultations tailored towards supporting health-promoting behaviors; and (2) a Cognitive Behavioral Therapy (CBT) intervention tailored towards addressing chronic stress that contributes to excess weight and maladaptive eating behaviors and results in obesity and CVD. Participants and their caregivers will be randomly placed into either the Lifestyle Medicine Group, CBT Group, or combined Lifestyle Medicine with CBT Group. Participants will respond to questionnaires and surveys measuring lifestyle habits, stress, and psychological risk factors at their first visit, 6-month visit, and 3 months post-intervention visit. Over the course of 6 months, participants will attend virtual sessions (up to three times a month) in accordance with their intervention group.

Eligibility criteria

Qualifiers

• Have a diagnosis of autism or be told by a healthcare provider that you have autism

Be between the ages of 9 and 26

Have a BMI greater than the 84th percentile

English speaking

Disqualifiers

• Children younger than 9 years of age

Adults older than 26 years of age

Individuals without a diagnosis of autism

Individuals with a BMI less than the 84th percentile

Trial design

Treatments tested in this trial

  • Lifestyle Medicine
  • Cognitive Behavioral Therapy (CBT)
  • Lifestyle Medicine with CBT Group

Treatment groups

130 Participants
are divided into 3 treatment groups

Locations

This trial has no locations

Sponsors and collaborators

University of California, Los Angeles

Lead sponsor

Health Resources and Services Administration (HRSA)

Collaborator