About this trial
This study will examine how different types of milk affect blood sugar and insulin responses after eating. Specifically, the study compares milk that contains only A2 beta-casein protein (A1-free milk) to conventional milk, which contains both A1 and A2 proteins.
Participants will complete four study visits in which they will consume different milk-based beverages. These include lactose-containing milk and lactose-free milk followed by a lactose drink given later. Blood samples will be collected over several hours to measure glucose and insulin responses. Breath tests and questionnaires will also be used to assess digestion and gastrointestinal symptoms.
The goal of this study is to determine whether milk protein type influences metabolic responses and whether consuming lactose-free milk affects how the body processes lactose when it is consumed later.
Eligibility criteria
Qualifiers
Ability/desire to provide informed consent
Are between 18 and 65 years of age
Are generally healthy, with no known metabolic or gastrointestinal conditions that would affect digestion or metabolism
Are willing to consume milk-based beverages and lactose-containing drinks as part of the study
Disqualifiers
You have a known allergy to milk or dairy products
You are currently pregnant, planning to become pregnant, or breastfeeding
You currently smoke or have used tobacco or nicotine-containing products within the past 3 months
You have a history of excessive alcohol use within the past 30 days
Trial design
Treatments tested in this trial
- Lactose-Containing A1-Free Milk
- Lactose-Containing Conventional Milk
- Lactose-Free A1-Free Milk With Delayed Lactose Drink
- Lactose-Free Conventional Milk With Delayed Lactose Drink