Ablation With Confirmation of Colorectal Liver Metastases (ACCLAIM)
ConditionColorectal Liver Metastases
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorSociety of Interventional Oncology
About this trial
To demonstrate that microwave ablation (MWA) of up to 3 hepatic metastases, each with a maximum diameter of ≤ 2.5 cm will result in a 2-year local progression free survival of at least 90%. This is a standard of care (SOC) study.
Eligibility criteria
Qualifiers
Patient must be at least 18 years old.
Patient has signed a written informed consent for the MWA and participation in the study.
Patient with pathologically confirmed CRC with hepatic metastases confirmed on imaging (e.g., CT or MRI).
Patient has up to 3 hepatic metastases, each up to 2.5 cm in largest diameter.
Disqualifiers
Patient is unable to lie flat or has respiratory distress at rest.
Patient has uncontrolled and uncorrectable coagulopathy or bleeding disorders.
Patient has a history of an allergic reaction to intravenous iodine that cannot be pre-medicated or prevents performance of a CT with IV contrast.
Patient has evidence of active systemic infection.
Trial design
Treatments tested in this trial
- Microwave ablation
Treatment groups
275 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov