Accelerated iTBS for Post Partum Depression
ConditionPost Partum Depression
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-50
SponsorMedical University of South Carolina
About this trial
Study 1: The investigators are studying the feasibility and tolerability of 10x/day intermittent theta burst (excitatory) transcranial magnetic stimulation to the left dorsolateral prefrontal cortex over the course of 6 days for women with post-partum depression. The investigators further aim to characterize the anticipated anti-depressant effect of this treatment paradigm.
Study 2: The investigators are studying the feasibility and tolerability of 12 sessions/day of intermittent theta burse (excitatory) transcranial magnetic stimulation to the left dorsolateral prefrontal cortex over 5 days for women with post-partum depression. The investigators aim to compare the two different treatment schedules.
Eligibility criteria
Qualifiers
Participants must be able to provide informed consent and function at an intellectual level sufficient to allow accurate completion of all assessment instruments.
Participants must be over the age of 18.
Participants must meet criteria for post-partum depression: a) onset of symptoms in the first year postpartum
Participants must have a HRSD17 greater than or equal to 14 at baseline.
Disqualifiers
Participants must not be pregnant.
Participants must not meet moderate or severe use disorder of any substance with the exception of Tobacco Use Disorder.
Participants must not have current psychotic symptoms.
Participants must not have a history of dementia or other cognitive impairment.
Trial design
Treatments tested in this trial
- iTBS
Treatment groups
40 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov