Accelerated Partial Breast Irradiation Versus Standard or Hypofractionated Whole-Breast Irradiation, in Early Breast Cancer, After Breast-conserving Surgery

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age50-90
SponsorInstituto Brasileiro de Controle do Cancer

About this trial

Radiotherapy has been confirmed as an important treatment breast-conserving surgery reducing the risk of any recurrence of breast cancer and breast cancer-related mortality in patients with early breast cancer.

There are no comparative data on the ideal radiotherapy treatment regimen for patients with early stage breast cancer who underwent conservative surgery in the Brazilian population.

Eligibility criteria

Qualifiers

Information to the patient and signed informed consent;

Women aged ≥50 years

Breast conserving surgery

Pathologic tumor size < 3 cm (maximum microscopic diameter of the invasive component)

Disqualifiers

Previous malignancy (except non-melanomatous skin cancer)

Mastectomy

Classical-Type Invasive Lobular Carcinoma

Neoadjuvant chemotherapy

Trial design

Treatments tested in this trial

  • Active Comparator: Standard
  • Experimental 1: Hypofractionated radiotherapy
  • Experimental 2: Accelerated Partial Breast Irradiation

Treatment groups

36 Participants
are divided into 3 treatment groups