Accelerated Partial Irradiation of the Breast: New Altered Fractionation

ConditionBreast Cancer
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age40+
SponsorFundación Pública Andaluza para la gestión de la Investigación en Sevilla

About this trial

The aim of this observational study is to evaluate a dose fractionation scheme for APBI using external radiotherapy with modulated intensity technique (IMRT), with the possible impact on the quality of life of patients as it decreases the treatment number of sessions and improves the efficiency and accessibility.

Eligibility criteria

Qualifiers

≥ 45 years or 40-44 if there isn´t any other risk factor

Diagnosed with infiltrating ductal carcinoma (IDC) or ductal carcinoma in situ (DCIS) and that have undergone conservative surgery without ganglionar involvement (pN0) of any histological degree except from invasive lobular carcinoma and with a size ≤ 3 cm.

Disease free margins (R0: > 2mm).

Positive and negative estrogen receptor tumors.

Disqualifiers

Multicentric and multifocal tumors, except from if it´s focal and the only risk factor.

Patients must not have undergone a neoadjuvant QT therapy.

Patients with BRCA positive mutation will be excluded.

Those patients unable or unsuitable to understand and accept the informed consent.

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

174 Participants
are grouped into 1 trial group