About this trial
This is an observational substudy embedded in the STEPCARE Trial. The study involves EEG analysis, covered by the ethics approval of STEPCARE Trial. The investigators aim to compare the accuracy of a continuously measured algorithm-based EEG index, C-Trend Index, with retrospective visual analysis of continuous EEG in predicting favorable functional outcome in adult patients treated in intensive care units after out-of-hospital cardiac arrest. The primary hypothesis is that the accuracy of C-Trend Index has at least 10% better accuracy in predicting favorable outcome than the visual analysis of cEEG, when assessed early, 9-12 hours after return of spontaneous circulation (ROSC).
Eligibility criteria
Qualifiers
Age 18 years or older
OHCA, with sustained ROSC
Unconscious after ROSC
No limitations to full life support
Disqualifiers
age <18
Previously randomized to STEPCARE
Trauma or hemorrhage as the reasons for arrest
Suspected or confirmed intracerebral hemorrhage
Trial design
Treatments tested in this trial
- C-Trend Index
Treatment groups
Sponsors and collaborators
University of Helsinki
Lead sponsor
Tampere University
Sponsor institution
University of Oulu
Collaborator
Skane University Hospital
Collaborator
Helsinki University Central Hospital
Collaborator
Kuopio University Hospital
Collaborator
Tampere University
Collaborator
Charite University, Berlin, Germany
Collaborator
Oslo University Hospital
Collaborator
Tampere University Hospital
Collaborator