Accuracy of PoCT to ELISA by Detecting Human IL-6 in Teeth with Apical Periodontitis

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age17-65
SponsorManipal University College Malaysia

About this trial

To compare the diagnostic agreement of human IL-6 chairside PoCT to ELISA in apical periodontitis undergoing endodontic therapy which could be clinically helpful to monitor the healing of periapical tissues enabling the clinician to complete the endodontic procedure, leading to a better patient care.

This study will be conducted at the Conservative and Endodontics Department in Polyclinic B, Faculty of Dentistry, Manipal University College Malaysia (MUCM). It involves 30 selected patients who have single rooted tooth with apical periodontitis that undergo RCT. The collection of the exudate from the canal will be on pre and post-instrumentation. The exudated will collect twice in each instrumentation for PoCT and ELISA.

Eligibility criteria

Qualifiers

Patient having single root tooth with AP that is negative to the pulp sensitivity test

Presence of periapical lesion

Disqualifiers

Pregnancy

Trial design

Treatments tested in this trial

  • Point of Care Test

Treatment groups

30 Participants
are divided into 1 treatment group

Sponsors and collaborators

Manipal University College Malaysia

Lead sponsor

Melaka Manipal Medical College

Sponsor institution

Melaka Manipal Medical College

Collaborator