To compare the diagnostic agreement of human IL-6 chairside PoCT to ELISA in apical periodontitis undergoing endodontic therapy which could be clinically helpful to monitor the healing of periapical tissues enabling the clinician to complete the endodontic procedure, leading to a better patient care.
This study will be conducted at the Conservative and Endodontics Department in Polyclinic B, Faculty of Dentistry, Manipal University College Malaysia (MUCM). It involves 30 selected patients who have single rooted tooth with apical periodontitis that undergo RCT. The collection of the exudate from the canal will be on pre and post-instrumentation. The exudated will collect twice in each instrumentation for PoCT and ELISA.
Patient having single root tooth with AP that is negative to the pulp sensitivity test
Presence of periapical lesion
Pregnancy
Patient who is having apical periodontitis and undergo RCT in MUCM
Other
Cross-sectional
Point of Care Test
DevicePoCT as a chairside test, ELISA as a gold standard
Detect the IL-6 in the exudate of the tooth with apical periodontitis
Collection of exudate in Pre-instrumentation for PoCT and ELISA . After 1 week, collection of exudate in post-instrumentation for PoCT and ELISA will be done.
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Manipal University College Malaysia
Lead sponsor
Melaka Manipal Medical College
Sponsor institution
Melaka Manipal Medical College
Collaborator
This trial is not recruiting at the moment. You can still explore other options:
