This is an observational, proof-of-concept, feasibility study where 30 preterm infants on bubble CPAP with gestational age \< 32+0 weeks will be recruited from the neonatal intensive care unit (NICU) at the Montreal Children's Hospital.
The study's main goals are:
1. To determine the relationship between ambient bubbling sounds and delivered pressures in preterm infants on bCPAP. 2. To determine the relationship between transmitted bubbling sounds and airway pressures transmitted to the lungs of preterm infants on bCPAP. 3. To develop models to predict delivered and transmitted bCPAP pressures from the acoustic properties of bubbling sounds.
Infants on bCPAP with gestational age < 32+0 weeks
Postmenstrual age between 28+0 and 36+6 weeks at the time of the study
Postnatal age greater than 168 hours (7 days) at the time of the study
On the bubble CPAP device with binasal prongs at the time of the study
Infants with known major congenital anomalies
Infants with known congenital heart disorders
Infants with known neuromuscular disease
Infants receiving ventilator-derived CPAP at the time of the study
McGill University Health Centre/Research Institute of the McGill University Health Centre
Lead sponsor
Northwestern University
Collaborator