Acquired Dyslexia Modeling and Treatment
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-85
SponsorRutgers, The State University of New Jersey
About this trial
This study is a low-risk, early phase 1, multicenter trial to test the use of a computational (neural network) cognitive model of reading to simulate acquired dyslexia and its treatment. The aim is to determine whether there is an advantage to receiving the treatment the model predicts to be advantageous compared to the alternative treatment. All participants will receive two full rounds of treatment. A round of treatment will consist of either phonomotor treatment (PMT) or semantic feature analysis (SFA) for 60 hours, distributed over 5 days a week for 2 hours a day.
Eligibility criteria
Qualifiers
Fluent in English as a first language pre-stroke by self report.
Normal or corrected-to-normal vision.
Normal or aided hearing.
Left hemisphere ischemic or hemorrhagic stroke (as verified by a structural brain scan).
Disqualifiers
Diagnosed pre-stroke neurological disease affecting the brain other than left hemisphere stroke.
Severe apraxia of speech (determined by consensus judgment among speech-language pathologists).
History of learning disabilities such as developmental dyslexia or current self-reported major psychiatric disorders.
Inability to undergo, or provide a copy of, a post-stroke brain imaging scan.
Trial design
Treatments tested in this trial
- Phono-Motor Therapy
- Semantic Feature Analysis
Treatment groups
12 Participants
are divided into 2 treatment groupsSponsors and collaborators
Rutgers, The State University of New Jersey
Lead sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
Collaborator
Source ClinicalTrials.gov