About this trial
The AHF-CODE preserved study is a prospective, non-randomized, monocenter study performed in patients with heart failure with preserved ejection fraction admitted for worsening heart failure.
The main objective of the AHF-CODE preserved study is to identify congestion markers (clinical, biological and ultrasound) at the end of hospitalization for acute heart failure that are associated with the risk of all cause death or rehospitalization for acute heart failure within 3 months of hospital discharge.
Eligibility criteria
Qualifiers
Patients hospitalised for acute heart failure.
Patient with preserved ejection fraction (FE ≥ 50%).
Patients considered clinically discharging from hospitalisation for acute heart failure.
Age ≥18 years
Disqualifiers
Comorbidity for which the life expectancy is ≤ 3 months
Dialysis patient (peritoneal dialysis or hemodialysis) or patients with glomerular filtration rate <15 ml/min/m² at inclusion.
History of lobectomy or pneumonectomy lung surgery
Severe pulmonary or pleural pathology preventing reliable acquisition of lung ultrasound images: severe emphysema, chronic pleurisy, pulmonary fibrosis, etc.
Trial design
Treatments tested in this trial
- Clinical examination centered on congestion
- Cardio-pulmonary, peritoneal, jugular and renal Doppler ultrasounds and liver elastography
- Biological: Blood sample retrieved for biological assessment and biobanking
- Telephone interview
- Kansas City Cardiomyopathy Questionnaire (KCCQ)