Acute Infectious Encephalitis and Myelitis in Guadeloupe by New Generation Sequencing

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age28+
SponsorCentre Hospitalier Universitaire de la Guadeloupe

About this trial

: Encephalitis or myelitis is defined as the inflammatory or infectious involvement of the cerebral parenchyma or spinal cord. When an infectious origin is suspected, the germ is not always identified. Next-generation sequencing could be used to correct an etiological diagnosis of these severe conditions in Guadeloupe. The rate of cases for which the infectious agent is not identified encourages continued diagnostic efforts, with the objective of identifying new pathogens or emerging pathogens, some of which may be more specific in the tropics.

Eligibility criteria

Qualifiers

Patient of at least 28 days of life

With acute onset of symptoms for more than 24 hours

a disorder of consciousness or alertness

memory disorder

Disqualifiers

Primary vasculitis of the central nervous system or a documented specific impairment in an autoimmune condition

Cerebral thrombophlebitis if not associated with encephalitis

Meningitis without clinical or paraclinical argument for cerebral parenchymal involvement

Pyogenic abscess

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

100 Participants
are grouped into 1 trial group