The objective of the study is to collect adaptive optics (AO) retinal images from human subjects with outer retinal diseases (diseases of the outer retina including photoreceptor, retinal pigment epithelium (RPE), basement membrane or choroidal pathologies) to develop new diagnostic methods, biomarkers, and clinical endpoints.
Are 21 years of age or older,
Have the ability to cooperate with instructions during adaptive optics imaging (similar to instructions given during a clinical eye exam),
Have the ability to understand and sign an informed consent. (Non-English speaking participants will not be enrolled into the study), and
Have been diagnosed with outer retinal disease or condition (Cohort 2).
Have a condition which prevents adequate images from being obtained (e.g. unstable fixation or media opacity),
Have visual correction outside of the range +4 diopters (D) to -8 D,
Have a history of adverse reaction to mydriatic drops,
Have a predisposition to (i.e., narrow iridocorneal angle) or any history of acute angle closure glaucoma (AACG), or
Food and Drug Administration (FDA)
Lead sponsor
National Eye Institute (NEI)
Collaborator