Adding Amantadine or Duloxetine to Pregabalin on Occurrence of Post Mastectomy Pain Syndrome
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-65
SponsorCairo University
About this trial
This study aims to evaluate the additive effect of Amantadine or Duloxetine to Pregabalin on development of post mastectomy pain syndrome
Eligibility criteria
Qualifiers
Age from 18 to 65 years.
American society of anesthesiologists (ASA) Physical status II, III.
Body mass index (BMI): (20-40) kg/m2.
Type of surgery: patients undergoing modified radical mastectomy for breast cancer.
Disqualifiers
Patient refusal.
Patients with Known sensitivity or contraindication to drug used in the study.
History of psychological disorders and/or chronic pain and drug abuse patients.
Previous administration of antidepressants, anticonvulsants, or opioids before surgery.
Trial design
Treatments tested in this trial
- Pregabalin
- Pregabalin + Amantadine
- Pregabalin + Duloxetine
Treatment groups
150 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov