Here, in our study, we intend to compare the analgesic efficacy of magnesium sulfate as an adjuvant to local anesthetics added to the Pecto-Intercostal Fascial Block (PIFB) vs the Serratus Anterior Plane Block (SAPB) in patients undergoing modified radical mastectomy.
Study Endpoints Primary Endpoints: Total intravenous opioid consumption during the first 24 hours following surgery. Secondary Endpoints: Postoperative analgesia, 24 hours after surgery, assessed using the Visual Analog Scale (VAS) and time to first analgesic request.
Female patients aged 30 to 75 years diagnosed with non-metastatic breast cancer and scheduled for modified radical mastectomy.
ASA, I-III and NYHA, I-II.
Written informed consent.
ASA physical status >III and NYHA >II,
body mass index >40 kg/m2,
pregnant women,
Patients with organ failure or coagulation disorders.
South Egypt Cancer Institute
Lead sponsor
Assiut University
Collaborator