Given the burden of chronic postmastectomy pain and the need for effective, opioid-sparing analgesia, the propose of the randomized controlled trial is to evaluate the safety and efficacy of adding magnesium sulphate to the combination of PIP block and ESPB in patients undergoing modified radical mastectomy for reducing acute and chronic post mastectomy pain
Female patients aged ≥18 years.
American Society of Anesthesiologists (ASA) class I-III.
Scheduled for unilateral modified radical mastectomy.
Known allergy to local anesthetics or magnesium.
Coagulopathy or anticoagulant therapy.
Local infection at injection site.
Body mass index (BMI) ≥ 40 kg/m2.
South Egypt Cancer Institute
Lead sponsor
Assiut University
Collaborator