Randomised, single-blind clinical trial comparing chlorhexidine gluconate-impregnated transparent dressings versus conventional transparent dressings in the prevention of central venous catheter-related bloodstream infections (CVC-BSI) in paediatric patients admitted to a tertiary hospital PICU. Outcomes include incidence of BRCVC, catheter colonisation, dressing-related skin complications, and number of dressing changes.
Admission to paediatric intensive care unit (PICU)
Central venous catheter placement (central or peripherally inserted)
Informed consent obtained from parent/legal guardian
Known immunological disorders
Neutropenia (<500/mm³)
Pre-existing colonisation or infection with multidrug-resistant organisms
University of Seville
Lead sponsor
Hospitales Universitarios Virgen del Rocío
Collaborator