Advancing Reperfusion Therapy for Ischemic Stroke: Direct Transfer to Angiography Suite for Patients With Suspected Large Vessel Occlusion

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorBeijing Tiantan Hospital

About this trial

The investigators initiated a multicenter, prospective, randomized, open-label, blinded-endpoint (PROBE) controlled trial to evaluate the efficacy and safety of the direct transfer to angiography suite (DTAS) triage strategy compared to the conventional triage strategy with CT/MRI in patients with suspected large artery occlusive (LVO) within 6 hours of symptom onset.

Eligibility criteria

Qualifiers

Age≥18 years old;

Patients presenting with symptoms or signs suggestive of acute large vessel occlusion (LVO) stroke;

Randomization within 6 hours of symptom onset;

Baseline NIHSS score ≥10 points prior to randomization;

Disqualifiers

Refusal of endovascular treatment;

Allergy to contrast agents;

Clinical symptoms or signs suggestive of intracranial hemorrhage (e.g., severe headache, seizures, or signs of increased intracranial pressure);

Transferred patients (e.g., from centers without thrombectomy capability);

Trial design

Treatments tested in this trial

  • direct transfer to angiography suite
  • conventional CT/MRI triage strategy

Treatment groups

568 Participants
are divided into 2 treatment groups

Sponsors and collaborators