Aerobic Exercise and Obsessive-Compulsive Disorder Symptoms
ConditionObsessive-Compulsive Disorder (OCD)
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-64
SponsorYale University
About this trial
The purpose of this study is to examine the acute effects of exercise on cognitive flexibility and symptom reactivity. The main questions it aims to answer are:
Does moderate intensity physical activity reduce subjective distress, compulsive urges, and intrusions- and increase cognitive flexibility- in adults with obsessive-compulsive disorder compared to low-intensity physical activity?
Researchers will compare low- to moderate-intensity exercise to see if moderate physical activity increases cognitive flexibility and reduces symptom reactivity in adults with obsessive-compulsive disorder (OCD).
Participants will:
Complete self-report surveys, psychiatric interviews, and cognitive tasks.
Be assigned to either a low- or moderate-intensity exercise condition and complete physical activity.
Repeat cognitive and symptom measures following the exercise intervention.
Eligibility criteria
Qualifiers
Adults, age 18 to 64 years
Meet diagnostic criteria for OCD (per the DIAMOND)
Stable psychiatric or medication treatment (if ≥4-weeks), or if no active treatment. Psychotropic medications will be reviewed with the study psychiatrist on a case by case basis.
Disqualifiers
Active or unmanaged psychotic disorders, pervasive developmental disorders, bipolar disorder, current substance use disorder (moderate-to-severe), or high risk for suicide (defined as attempt, plan, or intent within past 3 months)
Documented motor impairments and medical condition(s) that prohibit physical exercise
Those who are pregnant or trying to become pregnant
Trial design
Treatments tested in this trial
- Moderate-Intensity Exercise
- Low-Intensity Exercise
Treatment groups
50 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov