About this trial
The assisted reproduction success rate is affected by several factors including the age of the women, oocyte quality and maturation state, as well as sperm quality. Imaging of the meiotic spindle may be crucial for determining the oocyte maturation. Artificial intelligence (AI) will be applied to establish the complex oocyte quality, embryo ploidy and pregnancy success probability from the sequence of data, starting with the recording of the meiotic spindle in polarized light, through paternal factors up to the time lapse recording of early embryo development. This strategy should reduce the cost of fertility treatment thanks to increased efficiency in choosing the most promising candidates and reducing the need for costly laboratory analyses.
Eligibility criteria
Qualifiers
Intracytoplasmatic Sperm Injection
Preimplantation genetic testing
Time lapse embryo record
Singned informed consent
Disqualifiers
Gynecological diseases
Genetical diseases of parents
Trial design
Treatments tested in this trial
- arteficial inteligence evaluation of oocyte and embryo development
Treatment groups
Sponsors and collaborators
Charles University, Czech Republic
Lead sponsor
Czech Academy of Sciences
Collaborator
Czech Technical University in Prague
Collaborator
General University Hospital, Prague
Collaborator