AGEWISE: Unravelling the Gut-Hormone Axis in Women's Ageing

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age40-64
SponsorGulbenkian Institute for Molecular Medicine

About this trial

AGEWISE is an observational study that aims to understand how changes in gut microbiome are related to hormonal changes during women's ageing, particularly across the different stages of menopause. The study will include healthy women aged 40 to 64 years living in Portugal, who will provide stool and blood samples and complete questionnaires about their health, lifestyle, diet, and menopausal symptoms. Researchers will study the gut microbiome together with hormone levels and markers of inflammation to better understand how menopause affects long-term health and to support the development of improved prevention strategies for women.

Eligibility criteria

Qualifiers

Female sex

Aged 40 to 64 years

Resident in mainland Portugal or the islands

Able and willing to provide written informed consent

Disqualifiers

Age below 40 years or 65 years and older

Inability to give informed consent

Refusal to provide stool or blood samples or complete questionnaires

Pregnancy

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

300 Participants
are grouped into 3 trial groups

Sponsors and collaborators

Gulbenkian Institute for Molecular Medicine

Lead sponsor

Biocodex Microbiota Foundation

Collaborator