About this trial
It is a prospective, controlled, single-center, non-randomized, observational study. Two patient groups are planned for inclusion: the first - 200 patients with significant coronary artery stenosis confirmed by coronary angiography (CAG) or multislice computed tomography (MSCT) results; the second - a control group consisting of 200 patients without significant stenosis according to CAG or MSCT data.
All study subjects will have a date of coronary artery imaging via CAG or MSCT with assessment of myocardial perfusion.
Stress echocardiography tests or fractional flow reserve (FFR) assessment will be conducted as indicated.
All patients included in the study will undergo ECG recording within 1 month before or after CAG or MSCT in standard lead I for 1 minute, followed by spectral analysis of the obtained data, which will be stored at the remote monitoring center of Sechenov University without being linked to the personal data of patients. A spectral analysis of the electrocardiogram will be performed using a continuous wavelet transform.
The result of this study will be the identification of ECG parameters that correlate with significant coronary artery stenosis.
Eligibility criteria
Qualifiers
Presence of written informed consent from the patient to participate in the study.
Age 18 years and older.
Outpatient visit and/or hospitalization at the research center with coronary visualization performed.
Absence of sufficient data on coronary anatomy and stenosis significance.
Disqualifiers
Patient's unwillingness to continue participation in the study.
Inability to perform full analysis of single-channel ECG digital characteristics.
Refusal of coronary visualization methods for any reason.
Trial design
Treatments tested in this trial
- single-channel electrocardiogram