AI Prediction of Gastric Cancer Response to Neoadjuvant Chemotherapy

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorChinese Academy of Sciences

About this trial

This study seeks to develop a deep-learning-based intelligent predictive model for the efficacy of neoadjuvant chemotherapy in gastric cancer patients. By utilizing the patients' CT imaging data, biopsy pathology images, and clinical information, the intelligent model will predict the post-neoadjuvant chemotherapy efficacy and prognosis, offering assistance in personalized treatment decisions for gastric cancer patients.

Eligibility criteria

Qualifiers

Age 18 years or older;

Pathologically diagnosed with advanced gastric cancer in accordance with the American AJCC's TNM staging standards;

Have not undergone any systematic anti-cancer treatments before neoadjuvant chemotherapy and have not had surgery for local progression or distant metastasis;

Received standard neoadjuvant chemotherapy as recommended by the clinical guidelines, and have documented treatment details;

Disqualifiers

Patients whose CT or pathology images are unclear, making lesion assessment infeasible;

Patients diagnosed with other concurrent tumors.

Trial design

Treatments tested in this trial

  • Neoadjuvant Chemotherapy

Treatment groups

200 Participants
are divided into 1 treatment group

Sponsors and collaborators

Chinese Academy of Sciences

Lead sponsor

Institute of Automation, Chinese Academy of Sciences

Sponsor institution

Peking University Cancer Hospital & Institute

Collaborator

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Collaborator

Yunnan Cancer Hospital

Collaborator

Henan Cancer Hospital

Collaborator

Zhenjiang First People's Hospital

Collaborator

First Hospital of China Medical University

Collaborator

Cancer Hospital of Guangxi Medical University

Collaborator

Peking University People's Hospital

Collaborator

Tianjin Medical University Cancer Institute and Hospital

Collaborator

The First Affiliated Hospital of Zhengzhou University

Collaborator

Nanfang Hospital, Southern Medical University

Collaborator

The Affiliated Hospital of Qingdao University

Collaborator

Ruijin Hospital

Collaborator

Sixth Affiliated Hospital, Sun Yat-sen University

Collaborator

Peking Union Medical College Hospital

Collaborator

Xiangya Hospital of Central South University

Collaborator

Affiliated Cancer Hospital & Institute of Guangzhou Medical University

Collaborator

The First Affiliated Hospital of Soochow University

Collaborator

First Affiliated Hospital, Sun Yat-Sen University

Collaborator

Fujian Medical University Union Hospital

Collaborator

Fujian Cancer Hospital

Collaborator

San Raffaele University Hospital, Italy

Collaborator