AKI Risk Factors Analysis After Intentional Hypotensive Anesthesia

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-65
SponsorKaohsiung Medical University Chung-Ho Memorial Hospital

About this trial

This project investigates intentionally hypotensive management such as NTG (nitroglycerin) or NTG+Trandate during general anesthesia in patients undergoing orthognathic surgery. Throughout the entire surgical procedure, blood biochemical and urine monitoring will be conducted. Serum creatinine (Cr) levels, urine analysis, and perioperative monitoring will be utilized as indicators for assessing renal function during the surgery. The objective is to assess its potential renal injury and identify early risk factors for acute kidney injury (AKI). Timely recognition of these factors will allow for the implementation of appropriate intervention strategies, aiding in the prevention of postoperative acute kidney injury. This approach contributes to achieving the goals of Enhanced Recovery After Surgery (ERAS) for surgical patients, promoting faster postoperative recovery.

Eligibility criteria

Qualifiers

America society anesthesiologist classification class I to II patients undergoing oro-maxillo-facial surgery

unlimited mouth opening

Disqualifiers

patients with arthritis with limited mouth opening

persistent liver dysfunction

chronic renal insufficiency

body mass index ≧35 kg/m2.

Trial design

Treatments tested in this trial

  • Nitroglycerin

Treatment groups

No treatment groups listed