The goal of this natural history study is to learn more about the biological and clinical aspects of amyotrophic lateral sclerosis (ALS). This study's findings will help with drug discovery, biomarker discovery, and outcome measure validation. Adults living with ALS, other motor neuron diseases (MND), a known mutation related to ALS and healthy volunteers contribute prospective and retrospective data to this study remotely. The study is sponsored and conducted by the ALS Therapy Development Institute.
18 years of age or older
Can communicate in written English
Has a diagnosis of ALS/MND or is a known carrier of an ALS associated mutation
Significant cognitive impairment that would prevent individual completion and understanding of the informed consent process.