Alteration of Symbiosis Intestinal Microbiota on Patients With Anorexia Nervosa
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAssistance Publique - Hôpitaux de Paris
About this trial
The purpose of this study will be to study the association between the level of psychic symptomatic of anorexia nervosa (AN) (intensity of food restriction, symptoms of anxiety and depression) and alteration of host environment symbiosis and the mechanism (dysbiosis of intestinal microbiota, increase of intestinal permeability, immunity alteration and low-grade inflammation).
Eligibility criteria
Qualifiers
Patients aged ≥18 years;
Anorexia according to DSM-5 and CIDI (Composite International Diagnostic Interview);
Body mass index (BMI) (P/T2) < 15;
Hospitalization for nutrition rehabilitation;
Disqualifiers
Patients no-responding all criteria of DSM-5 or CIDI scores;
Taken of antibiotic treatment 2 months / or laxativ 3 weeks before hospitalization;
Somatic comorbidity should perturb intestinal microbiota (Crohn's disease, diabetes and all other chronic inflammatory diseases);
Patients under guardianship;
Trial design
Treatments tested in this trial
- Stool and blood samples
Treatment groups
120 Participants
are divided into 2 treatment groupsSponsors and collaborators
Assistance Publique - Hôpitaux de Paris
Lead sponsor
Fondation de France
Collaborator
Source ClinicalTrials.gov