Alternative ProtEin Satiety Study (APES Study)

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age21-50
SponsorSingapore Institute of Food and Biotechnology Innovation

About this trial

This project aims to study the effects of different protein quality (i.e. high vs. low) and protein sources (i.e. plant protein vs. conventional animal protein) on post-meal satiety and satisfaction. The protein quality score of meals will be calculated using the published digestible indispensable amino acid score (DIAAS). The proposed study will investigate the link between protein quality, protein source, and the post-meal satiety responses, using a realistic lunch meal approach, in humans. Other than the self-reported visual analogue scale (VAS) satiety response, the postprandial glucose dips (i.e. 2-3hours post-meal) will be collected by continuous glucose monitoring (CGMS) as an objective indicator of postprandial self-reported hunger and subsequent energy intake. In addition, the oral processing behaviours of participants will be captured and compared between the test meals.

Eligibility criteria

Qualifiers

Healthy male

Aged between 21 and 50-year-old

Are of normal weight (BMI 18-25kg/m2)

Stable weight for the previous 12 months (<5kg weight fluctuation in the previous year)

Disqualifiers

Are a smoker

Have any dislikes, intolerances or allergies to foods or common food ingredients e.g. nuts, soya, wheat, gluten, cereal, fruits, biscuits, dairy products, rice, vegetable, meat, seafood, sugar and sweetener, gelatin, natural food colourings or flavourings (e.g. MSG), etc.

Have any specific dietary requirements and/ or restrictions (e.g. Vegan/ vegetarian, religious beliefs, lactose intolerance, calorie restricted diet etc.)

Known sensitivity to medical-grade adhesives

Trial design

Treatments tested in this trial

  • Behavioral: Post- meal satiety and subsequent ad-libitum meal energy intake

Treatment groups

50 Participants
are divided into 3 treatment groups

Locations

This trial has no locations