Aluminum Foil Reflector on Phototherapy for Newborn with Jaundice

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age1-14
SponsorTaipei Medical University Shuang Ho Hospital

About this trial

Hyperbilirubinemia is defined as the presence of bilirubin in the serum of newborns at levels exceeding the normal range. It is the most common problem among healthy newborns, with an incidence of approximately 40% to 60% in full-term infants. The primary cause is the immature bilirubin metabolism in newborns, leading to the accumulation of excess bilirubin in the blood, which in turn results in a temporary yellowing of the skin and sclera, known as jaundice. Physiological jaundice in full-term newborns typically appears 24 to 72 hours after birth, peaking on days 4 to 5. Studies have shown that neonatal jaundice is a leading cause of readmission after discharge.

Phototherapy is the most effective and safest treatment for neonatal hyperbilirubinemia. It takes advantage of bilirubin's sensitivity to light, converting bilirubin into water-soluble conjugated bilirubin, which is then excreted through bile and urine, thereby reducing total bilirubin levels. The most effective light during phototherapy has a wavelength of 400 nm to 520 nm and an intensity of at least 30 microW/cm²/nm, with at least 80% of the infant's body surface area exposed.

This study aims to investigate whether using aluminum foil reflective covering around the phototherapy incubator can enhance the effectiveness of light treatment for jaundice in infants, thus potentially reducing the duration of phototherapy required.

Eligibility criteria

Qualifiers

Newborns who are admitted to the neonatal ward for examination and treatment due to jaundice levels reaching the treatment threshold.

Term babies below 14 days of age (gestational age of 37 weeks or greater).

No evidence of hemolysis

Disqualifiers

Infants with serum bilirubin levels close to the exchange transfusion limit

Hemolytic disease (Ex: G6PD)

Congenital anomalies

Elevated direct bilirubin

Trial design

Treatments tested in this trial

  • Aluminum Foil Reflector

Treatment groups

160 Participants
are divided into 2 treatment groups