Amino Acid Loss During Continuous Renal Replacement Therapy

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorMedical University of Vienna

About this trial

The goal of this observational study is to learn about amino acid loss during continuous renal replacement therapy and plasma amino acid levels in intensive care patients. The main questions it aims to answer are:

What amount of amino acids is lost over the duration of continuous renal replacement therapy? How do amino acid plasma concentrations change over time in patients with and without continuous renal replacement therapy?

Amino acid concentrations will be measured in the effluent and in the plasma of patients receiving continuous renal replacement therapy as part of their regular medical care. In addition, plasma concentrations of amino acids will be studied in patients without renal replacement therapy.

Eligibility criteria

Qualifiers

Postoperative ICU patients

Age ≥ 18 years

Patients on enteral or/and parenteral nutrition given according to internal standard operating procedure

no current or previous (<30 days) continuous or intermittent RRT

Disqualifiers

Preoperative intensive care patients

Patients with liver cirrhosis stage 1-3 according to the Child-Pugh classification

Patients with acute liver failure

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

30 Participants
are grouped into 2 trial groups

Sponsors and collaborators

Medical University of Vienna

Lead sponsor

Karolinska Institutet

Collaborator