About this trial
The goal of this observational study is to learn about amino acid loss during continuous renal replacement therapy and plasma amino acid levels in intensive care patients. The main questions it aims to answer are:
What amount of amino acids is lost over the duration of continuous renal replacement therapy? How do amino acid plasma concentrations change over time in patients with and without continuous renal replacement therapy?
Amino acid concentrations will be measured in the effluent and in the plasma of patients receiving continuous renal replacement therapy as part of their regular medical care. In addition, plasma concentrations of amino acids will be studied in patients without renal replacement therapy.
Eligibility criteria
Qualifiers
Postoperative ICU patients
Age ≥ 18 years
Patients on enteral or/and parenteral nutrition given according to internal standard operating procedure
no current or previous (<30 days) continuous or intermittent RRT
Disqualifiers
Preoperative intensive care patients
Patients with liver cirrhosis stage 1-3 according to the Child-Pugh classification
Patients with acute liver failure
Trial design
Treatments tested in this trial
- Not listed
Trial groups
Sponsors and collaborators
Medical University of Vienna
Lead sponsor
Karolinska Institutet
Collaborator