Amino Acid Supplementation in Continuous Renal Replacement Therapy
ConditionAcute Kidney Injury
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorKarolinska University Hospital
About this trial
ICU patients treated with continuous renal replacement therapy is recruited prior to start of treatment.
Blood samples are drawn and then dialysis start without amino acid supplementation. After a few hours samples are drawn from blood and dialysate. Then patients are given amino acid supplementation (33.5g/24hrs) for 20-24 hours. New samples are drawn and amino acid supplementation is increased to 67g/24hrs and new samples are drawn after additional 24 hours. Then CRRT will continue with the full amino acid supplementation (standars of care).
Eligibility criteria
Qualifiers
Dialysis where amino acid supplementation is planned by treating physician
Disqualifiers
Liver failure
Muscle disease
Neurodegenerative disease
Trial design
Treatments tested in this trial
- Amino acid supplementation (Glavamin, Fresenius Kabi)
Treatment groups
30 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov